- Microarray technology is still new, but has been used in a variety of fields that are significant in general microbiology as well as in industrial microbiology and biotechnology, including disease detection, drug discovery and toxicological testing.
- In studying gene expression, microarrays are particularly useful. By leveraging the ability of a given mRNA molecule to bind directly to or hybridise to the DNA template from which it originated, a microarray operates.
- It is possible to establish, in a single experiment, the expression levels of hundreds or thousands of genes inside a cell by calculating the amount of mRNA bound to each site on the array by using an array containing several DNA samples.
- The amount of mRNA attached to the spots on the microarray is precisely determined with the assistance of a computer, producing a gene expression patterns in the cell.
- The bioactive potential of a particular microbial metabolite as a beneficial material in the form of a drug or its deleterious effect can thus be determined.
- If microarray studies detect a diseased condition, tests can be designed to be able to identify compounds from microbial metabolites or other origins that may boost or reverse the diseased condition
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