- Prokaryotic translation occurs on 70s ribosomes whereas eukaryotic translation occurs on 80s ribosomes.
- mRNA is polycistronic in prokaryotes whereas it is monocistronic in prokaryotes.
- Prokaryotic translation involves initiation factors :IF1 ,IF2 and IF3 whereas eukaryotic translation involves elF complex proteins.
- Prokaryotes requires releasing factors RF1 and RF2 and RF3 .Eukaryotes requires eRFs.
- Translation in both occurs in the cytoplasm.
- Protein synthesis occurs in ribosomes in both .